PRECIPITIN STUDIES IN NEPHROSIS AND NEPHRITIS

Mortality from nephritis and nephrosis in the fibreglass manufacturing industry.

OBJECTIVES To investigate the question of whether there is an association between exposure to silica or respirable glass fibre and mortality from nephritis or nephrosis among workers in fibrous glass wool manufacturing facilities. METHODS A case-control study with cases and controls derived from the Owens Corning mortality surveillance system. Two case-control analyses were carried out, one w...

Immunological studies in congenital nephrosis.

Studies on the Precipitin Reaction

1. Partial hydrolysis products of the specific polysaccharide of Type III pneumococcus ranging from 550 to 1,800 in formula weight can be quantitatively freed from unhydrolyzed polysaccharide. 2. The fractions yield specific precipitates with Type III antipneumococcus horse serum but fail to precipitate homologous rabbit antisera, giving rise only to specific inhibition. The aldobionic acid, th...

Quantitative Studies of Brucella Precipitin Systems

Quantitative cross precipitation studies with goat antisera show the three endoantigens of the brucella to be serologically distinguishable. Although the endoantigens of Br. abortus and Br. suis are very similar, they do not react identically, permitting the serological distinction of the two organisms. These differences in cross precipitation may be used to identify an organism of the brucella...

Quantitative Studies on the Precipitin Reaction

1. Antisera to R-salt-azo-benzidine-azo-crystalline egg albumin give precipitates with crystalline egg albumin by virtue of their antidye content. 2. The quantitative course of the reactions with increasing amounts of antigen is very similar for the dye-antidye and egg albumin-anti-egg albumin systems, but differs markedly for the cross reaction between egg albumin and antidye. 3. A possible ex...